| PhaSepDB ID | mlolt148 | Uniprot Entry | P35637 | Gene names | FUS |
|---|---|---|---|---|---|
| Class | MLO-lt | MLO | Paraspeckle | Organism | Homo sapiens |
| Cell line | HeLa cells | Method | _ | PMID | 33709256,22960638 |
| Publication note | To address the precise molecular processes that lead to paraspeckle formation, we identified 35 paraspeckle proteins (PSPs), mainly by colocalization screening with a fluorescent protein-tagged full-length cDNA library. Most of the newly identified PSPs possessed various putative RNA-binding domains. Subsequent RNAi analyses identified seven essential PSPs(NONO, SFPQ, RBM14, HNRNPH3, HNRNPK, DAZAP1 and FUS) for paraspeckle formation. | ||||